Systhesis of 2-Imino-5-arylmethylene-4-thiazolidinone derivatives

Abstract

Five compounds of2-imino-5-arylmethylene-4-thiazolidinones have beensynthesized from reaction of 5-arylmethylenerhodanines withhydroxylamine, aniline and phenylhydrazine. Among thesynthesized compounds, only the 2-phenylimino and2-phenylhydrazine derivatives could be synthesized from5-benzylidenerhodanine, while the products from otherrhodanines were unseparable. Evidences from infraredspectroscopy, H-NMR spectroscopy and mass spectroscopyconfirmed that the reactions between 5-arylmethylene-rhodanines and hydroxylamine, aniline and phenylhydrazinetook place at the carbon atom at position 2 of thiazolidinering.