Oral candida in denture stomatitis

Abstract

This thesis describes a study of oral Candida in three groups of subjects. The first group, Group 1, consisted of 76 healthy dental students: the second group, Group 2, consisted of 27 healthy denture wearers with clinically healthy mucosa; and the third group, Group 3, consisted of 40 denture wearers with denture stomatitis. The purpose is to find candidal incidence in the three groups of subjects by imprint cultures and salivary samples. The study shows that imprint cultures had a higher sensitivity than did salivary samples. After isolated yeasts had been cultured by imprint cultures, it was found that the oral candidal incidences for Group 1, Group 2, and Group 3 were 60.53%, 77.77%, and 100%, respectively; and the average for the overall subjects was 74.83%. Investigated Candida in male and female subjects had no significant difference, as indicated by p <0.05. Most of the identified candida was Candida albicans whose incidence was found to be 60.14% for the overall subjects. Other Candida cultures found with lower incidences were c. tropicalis (22.38%), C. parapsilosis (16.08%). C. krusei (4.2%). C. guilliermondii (0.63%). and C. species (1.4%). Besides, there were other yeasts found with low incidences: T. glabrata (5.59%), Trichosporon (2.1%, and Rhodotorula (1.4%). The study also indicates that the distribution of Candida varied with the site in the oral cavity, and that the dorsum of the tongue was where the isolated yeasts were found with highest incidence: 86.96% for Group 1, 85.71%. for Group 2, and 97.50% for Group 3. The mean density of oral Candida found in Group 3 was significantly higher than those in Group 1 and Group 2. Although Group 2 had a higer mean density of oral Candida than Group 1, there was no significant difference between two groups (p <0.05).