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Now showing items 1-20 of 94

Analysis of influenza a genomes and bacterial microbiota in upper respiratory tracts of influenza patients

Somruthai Rattanaburi (Chulalongkorn University, 2021)

Seasonal influenza is a contagious respiratory illness caused by influenza viruses that infect the upper respiratory tract (URT) of humans and represent a major burden for public health. Furthermore, the URT is colonized ...
Application of FTIR spectroscopic and mass spectrometric techniques for the investigation of the alteration in erythrocyte contents and phospholipids subspecies of type 2 diabetic patients after oral high fat loading

Sukrit Sirikwanpong (Chulalongkorn University, 2009)

It is well recognized that postprandial dyslipemia is an inherent feature of diabetic dyslipidemia highly prevalent in type 2 diabetic patients (T2DM) even with normal fasting triacylglycerol (TG) level. In addition, several ...
Argonaute 4 promotes genomic methylation

Kanwalat Chalertpet (Chulalongkorn University, 2019)

RNA-directed DNA methylation (RdDM) is the major small RNA-mediated epigenetic pathway in plants. Similar to genome and epigenome editing with the CRISPR-Cas9 system, RdDM is composed of a regulatory protein and a “guide” ...
ARGONAUTE 4 PROTEINS MEDIATE SMALL-RNA-GUIDED DE NOVO METHYLATION IN HUMAN CELLS

Piyapat Pin-on (Chulalongkorn University, 2014)

Argonaute proteins (AGOs) are evolutionarily conserved and ubiquitously expressed in all higher eukaryotes and have important function in several biological processes, such as cell differentiation and transposon silencing. ...
Autologous foot and ankle stem cell applications for lower extremity reconstruction surgery

Daniel Lee (Chulalongkorn University, 2011)

The objectives of this study were to examine the novel applications of stem cells for lower extremity reconstructive surgeries. This innovative modern new approach has little to scarce findings in literature. Even the ...
BHK-cell adapted canine rabies virus variant : mutation in intergenic phosphoprotein and matrix protein gene non-coding region may confer higher neurovirulence in adult mice

Phatthamon Virojanapirom (Chulalongkorn University, 2011)

Attenuation of rabies virus can be achieved by passaging virus into non-neuronal cells or by modification of genetic element(s). Following serial passages of Thai canine street rabies virus, QS-05, into BHK-21 cells, gave ...
Bone Marrow Aspirate derived stem cells for chronic wounds of the lower extremity

Mulder, Gerit (Chulalongkorn University, 2011)

The use of stem cells in chronic and problematic wounds is of particular interest as chronic wounds, particularly those of a diabetic nature, are a physical, social and financial drain to both the patient and the medical ...
The cervical disc dimensions of Thai population

Udthapon Wandee (Chulalongkorn University, 2008)

The incidence of complications with cervical disc arthroplasty was 6.2% per treat level. The perioperative kyphosis, heterotopic ossification and migration may be occurred due to undersized prosthesis. Measurement of ...
Characteristics of naïve CD4⁺T cells recognized staphylococal enterotoxin b superantigen presented by naïve B cells versus monocyte-derived dendritic cells

Kaj Chokeshai-u-saha (Chulalongkorn University, 2011)

To determine role of human naïve B cell in antigen presentation and stimulation to naïve CD4⁺T cell. To improve the yield and purity of human naïve B cell sepration, we have shown that inclduing B cell enrichment rosetting ...
Characterization and property investigation of novel human glucose 6-phosphate dehydrogenase inhibitors in lung cancer cell lines

Makamas Chanda (Chulalongkorn University, 2022)

G6PD plays fundamental roles in many cellular processes, including redox balance and lipid and nucleotide synthesis. Overexpression of G6PD is required to promote the proliferation and survival of cancer cells, including ...
Characterization of aberrant mTOR signaling pathway in U87MG glioblastoma cell line by quantitative phosphoproteomics

Nuttiya Kalpongnukul (Chulalongkorn University, 2021)

Glioblastoma (GBM) is one of the most damaging primary brain tumors with a poor prognosis. GBM is associated with an abnormality of the mTOR signaling pathway, consisting of two distinct kinase complexes: mTORC1 and mTORC2. ...
Characterization of the hypoglycemic effect of Gymnema inodorum and association study of rage gene polymorphisms and diabetic complication in Thai population

Anchalee Chiabchalard (Chulalongkorn University, 2008)

The effects of Gymnema inodorum (GI) tea consumption on glucose absorption and liver toxicity were evaluated in this study. The study was done in 73 healthy subjects of both sexes, aged between 18-25 years, who have normal ...
Chemically targeted-lysine modifications of erythropoietin : erythropoiesis and reno-protective effect of lysine modifie derythropoietin molecules

Supreecha Chattong (Chulalongkorn University, 2012)

Recombinant human erythropoietin (rHuEPO) is currently used for renal anemia treatment. Recently, rHuEPO has been shown to provide pleiotrophic tissue protection in various pathologic conditions. The benefits of rHuEPO ...
Deprogramming senescence by genomic stabilizing molecules in vivo

Sakawdaurn Yasom (Chulalongkorn University, 2021)

Aging is the inevitable, time-dependent, natural process in all living cells, resulting from the accumulation of cellular damage with insufficient cell repair. Global hypomethylation and Alu (B1) hypomethylation become ...
Detection of aberrant SHP-1 promoter 2 methylation, an implication in advanced non-small cell lung cancer

Chanida Vinayanuwattikun (Chulalongkorn University, 2010)

Backgroung: Under physiological conditions, leukocytes contribute to the majority of circulatng DNA in plasma. Therefore, detection of SHP-1 promoter-2 (SHP1P2) methylaton to represent epithlial tumor-derived circulatng ...
Development of a device for postural change while sitting for the prevention of neck or low back pain in office workers

Nipaporn Akkarakittichoke (Chulalongkorn University, 2021)

The objective of this thesis was to develop a device for postural change while sitting for the prevention of neck or low back pain in office workers. This thesis was divided into four stages: 1) to evaluate the effects of ...
Development of distance paper-based devices and electrochemical sensors for food and cosmetic safety assessment

Kasinee Katelakha (Chulalongkorn University, 2020)

This study aimed to integrate analytical techniques for supporting the safety assessment in food and cosmetics. The two analytical methods were proposed, including i) the development of the paper-based device for the ...
Differential expression of proteins in the central nervous system of early and late stage rabies infected dogs

Sangchai Yingsakmongkon (Chulalongkorn University, 2016)

Rabies is a zoonotic disease. Dogs are an important reservoir host of rabies in Thailand, Asia, Africa and Europe. The clinical manifestations are the same in humans and dogs, and are categorized into 2 forms; furious and ...
Ecosystem function assessment and participatory modelling for community forest management at Lainan Subdistrict, Wiang Sa District, Nan Province

Wuthiwong Wimolsakcharoen (Chulalongkorn University, 2019)

Community forest management (CFM) is one way used to mitigate deforestation and forest degradation which have been occurring for more than half a century, particularly in northern Thailand. The collaboration in CFM, ...
Effect of extracellular environmental factors in cholangiocarcinoma cells invasiveness

Suthidarak Chaijan (Chulalongkorn University, 2011)

The function of the extracellular matrix (ECM) in the tumor microenvironment is not limited to forming a barrier against tumor invasion. As demonstrated in pathological specimens, cholangiocarcinoma samples display an ...

Now showing items 1-20 of 94

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