Abstract:
Swine Influenza Virus (SIV) causes respiratory disease in pigs and can be found in pigs worldwide. This study provided the information on the occurrence, subtype and serological profiles of SIV infection in Thailand during 2011-2012. Seven hundred and forty-five nasal swab samples and 571 serum samples of Thai pigs were collected for SIV surveillance during September, 2011 – March, 2012. The result showed that 186 nasal swab samples (24.97%) were positive for influenza A virus by real-time RT-PCR, however only 13 samples (1.74%) were successfully isolated. For subtype identification, SIV subtype H1N1 (n=10) and H1N2 (n=3) were identified. For serological analysis, 262 serum samples (45.88%) were positive by NP-ELISA. HI test showed specific antibodies to swH3N2 (15.41%; 88/571), swH1N1 (2.45%; 14/571) and pH1N1 (4.90%; 28/571) in pig serum tested. In conclusion, our results indicated that during 2011-2012, SIV subtype H1N1 and H1N2 were circulating in Thai pig populations and the endemic SIV-H1N1 was the dominate SIV subtype in Thailand. The information gained from this study can be used for SIV prevention and control in pig and human populations.