Abstract:
Introduction : The purposes of this retrospective study were to compare the clinical and radiographic outcomes of mineral trioxide aggregate apexification and regenerative endodontics in non-vital immature permanent teeth, and to analyze factors influencing treatment outcomes. Method : Forty six cases were recruited into this study. Patients’ preoperative and postoperative information was analyzed. Treatment outcomes were categorized as success or failure, and functional retention. Further root development was assessed in terms of the percentage changes in root length and root width. Results : The success rate of mineral trioxide aggregate apexification and regenerative endodontics were 80.77% and 76.47% and functional retention was 82.76% and 88.24% respectively. Regenerative endodontics provided significant greater percentage changes in root width (13.75%) in comparison to MTA apexification (-3.30%). The mean percentage change of increased root length was 9.51% in regenerative endodontics group and 8.55% in MTA apexification group. Interestingly, regenerative endodontics showed various degree of increased root length ranging from -4 to 58%. Fracture was the main cause of failure in MTA apexified teeth. All failed regenerative endodontic teeth presented with signs and symptoms of apical periodontitis caused by persistent infection. Conclusion : MTA apexification and revascularization provide reliable outcome in the aspects of resolution of the disease and tooth functional retention. None of these treatments provides satisfactory predictable further root development.
