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Establishment of transplantation platform for delivering mouse induced pluripotent stem cell-derived insulin-producing cells (mips-ipcs) for diabetes treatment

Hong Thuan Tran (Chulalongkorn University, 2022)

Pancreatic beta-cell replacement is recognized for feasible type 1 diabetes (T1D) treatment. However, in post-transplantation, the autoimmune destruction incidentally attacks the activity and survival of beta-cells are ...

Metaproteomic analysis of gut resistome in the cecal microbiota of fattening pigs raised without antibiotics

Pamornya Buthasane (Chulalongkorn University, 2022)

Improper use of antibiotics in swine could reduce commensal bacteria and possibly increase pathogen infections via the gut resistome. This study aimed to compare the metaproteomic profiles of gut resistome and related ...

Prevalence and molecular characteristics of antimicrobial resistance of Aeromonas hydrophila, Salmonella spp., Vibrio cholerae, fecal coliform, and Escherichia coli in hybrid red tilapia and cultured water

Varangkana Thaotumpitak (Chulalongkorn University, 2021)

Foodborne pathogens and antimicrobial resistant bacteria in tilapia and cultivation water has been emerged as a public health threat. This study aimed to determine the prevalence of indicator and pathogenic bacteria in ...

Molecular characterization and antimicrobial susceptible profiles of Thai mycoplasma synoviae and immune response chickens received live mycoplasma synoviae vaccine

Kriengwich Limpavithayakul (Chulalongkorn University, 2022)

Mycoplasma synoviae infection in chickens which has been increasing worldwide is mostly controlled by pathogen-free flocks’ maintenance, medication in infected flocks and vaccination in high-risk flocks. The effective ...

Role of KCa3.1 channel on renal fibrosis in Doxorubicin-induced feline kidney cell line

Penpicha Kuedbantakien (Chulalongkorn University, 2022)

Feline renal fibrosis is the most common outcome of chronic kidney disease in cats. Nowadays, there is no specific treatment and the mechanism of fibrosis in cats is still unknown. Intermediate conductance Ca2+ activated ...

Estimating canine distemper virus exposure in captive carnivores in Thai zoos using a pseudotype-based serum neutralization test

Erngsiri Kaewkhunjob (Chulalongkorn University, 2022)

Despite its name, Canine distemper virus (CDV) infection is not restricted to canids but extends to several species of the order Carnivora. The extent of CDV exposure in captive carnivores in Thailand has never been estimated ...

Efficacies of Thai probiotic strains against antibiotic resistance bacteria and modulate gut microbiome and resistome in pig model

Prasert Apiwatsiri (Chulalongkorn University, 2021)

Lactic acid bacteria (LAB) have been widely used as probiotics in the livestock industry because of their high potential for antibacterial activity, anticonjugation, antibiofilm capacity, and gut microbiome regulation. ...

Selection of candidate probiotic bacteria from chickens with antagonism against campylobacter

Sirawich Danwanichwong (Chulalongkorn University, 2021)

Campylobacter is one of the most common causes of bacterial foodborne disease in humans worldwide. The effect of probiotics on Campylobacter control in poultry is inconsistent or rarely observed. For this reason, research ...

Genome characterization of quinolone resistance associated genes of flavobacterium columnare isolated from columnaris diseased asian sea bass (lates calcarif)ER)

Putita Chokmangmeepisarn (Chulalongkorn University, 2018)

Flavobacterium columnare is Gram negative bacteria which caused columnaris disease in various kinds of freshwater fishes. This study is the first report of F. columnare infection in freshwater culturing Asian sea bass in ...

Surveillance of influenza a viruses in a live bird market, Yangon, Myanmar during 2017-2018

Khin Thurain (Chulalongkorn University, 2018)

Live bird markets play a significant role in highly pathogenic avian influenza (HPAI) virus spread and transmission. In Myanmar, the first HPAI-H5N1 outbreak was reported in 2006. Since 2014, routine influenza A virus ...

Development of Elisa for detecting antibody against Bartonella spp. specific protein in cats and its application in natural infection

Krissda Boonaramrueng (Chulalongkorn University, 2021)

This study aims to evaluate the risk factor and an association between Bartonella spp. infection and immune status by using retroviral-infected cats as an immunocompromised model and to develop the recombinant B. henselae ...

Evolution and phylogenetic studies of porcine epidemic diarrhea virus and porcine Deltacoronavirus in Thailand from 2008 to 2021

Christopher James Stott (Chulalongkorn University, 2022)

PEDV and PDCoV are recognized as important pathogens causing enteric disease in swine herds worldwide. During 2014-2015, several outbreaks of PEDV occurred in many provinces in Thailand, and the clinical signs were more ...

Biomechanical and biological properties of cryopreserved canine amniotic membrane

Nathawan Withavatpongtorn (Chulalongkorn University, 2018)

Amniotic membrane (AM) is the innermost fetal membrane. Due to its many known properties, human AM is a favorable corneal graft. Cryopreservation at -80ºC maintains most of biological properties. Due to shortage of supply, ...

The efficiency of pcso-524 on feline osteoarthritis associated with chronic kidney disease

Pemika Dulyapraphant (Chulalongkorn University, 2018)

Twenty-six osteoarthritic cats concurrent with chronic kidney disease (CKD) enrolled in this study. All cats were divided randomly into 2 groups; control group (n=12) received placebo and treatment group (n=14) received ...

Associations of feline paramyxoviruses with pathological lesions in cat kidneys

Aisyah Nikmatuz Zahro (Chulalongkorn University, 2022)

Paramyxoviruses in cats composing of feline paramyxovirus (FPaV), feline morbillivirus genotype 1 (FeMV-1), and feline morbillivirus genotype 2 (FeMV-2). These viruses had been recently suggested to be associated with ...

Seroprevalence of Lawsonia intracellularis antibody among swine herds in Thailand, December 2021-March 2022

Thanh Nguyen Che (Chulalongkorn University, 2022)

The gastrointestinal infectious diseases caused by bacteria have been a major problem in the Thai swine industry. Porcine proliferative enteropathy (PPE), also known as porcine ileitis, is an enteric infectious disease ...

Recovery of isolated pancreatic isletsderived from gut leak-induced diabetes type ii mouse model

Adretta Soedarmanto (Chulalongkorn University, 2020)

Gut leak in the obese patient was known to be one of the predisposing factors causing diabetes type II. Indeed, the interleukin-10 (IL-10) plays a key role in gut mucosa homeostasis preventing the gut leak. Nevertheless, ...

Monitoring and characterization of colistin resistant Escherichia coli in pig farm and environment following the cessation in use of colistin

Nwai Oo Khine (Chulalongkorn University, 2021)

The growing cases of colistin resistance due to plasmid mediated mcr genes family in Enterobacteriaceae is catastrophic to public health. In this study, our team performed the nation-wide surveillance of mcr-positive ...

Therapeutic efficacy of subconjunctival injectionof canine adipose-derived mesenchymal stem cells on canine spontaneous chronic corneal epithelial defect

Pechchalee Kengkla (Chulalongkorn University, 2022)

Spontaneous chronic corneal epithelial defects (SCCEDs) are important corneal injuries in dogs. Canine adipose-derived mesenchymal stem cells (cAD-MSCs) was used for treatment of various types of corneal ulcers in dogs. ...

Anti-proliferative and apoptotic effect of cannabinoids on human pancreatic ductal adenocarcinoma xenograft in BALB/c nude mice model

Quang Trung Le (Chulalongkorn University, 2022)

Human pancreatic ductal adenocarcinoma (PDAC) is a highly malignant and lethal tumor of the exocrine pancreas. Cannabinoids extracted from the hemp plant Cannabis sativa have been suggested as a cancer therapy due to their ...

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