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First episode of preschool wheeze requiring hospitalization: a prospective study on the chance of recurrence and associated factors

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dc.contributor.author Karaked Chantawarangul
dc.contributor.author Jitladda Deerojanawong
dc.contributor.author Suchada Sritippayawan
dc.contributor.other Chulalongkorn University. Faculty of Medicine
dc.date.accessioned 2019-05-12T11:48:22Z
dc.date.available 2019-05-12T11:48:22Z
dc.date.issued 2018-12
dc.identifier.citation Asian Pacific Journal of Allergy and Immunology. Vol.36, Issue 4 (Dec, 2018), p. 232-237. en_US
dc.identifier.issn 0125-877x
dc.identifier.issn 2228-8694
dc.identifier.uri http://cuir.car.chula.ac.th/handle/123456789/61733
dc.description.abstract Background: Although wheezing is very common in preschoolers, epidemiologic studies in Thailand are quite limited. The likelihood of having a second wheezing episode following the first attack remains unclearly established. Objectives: This study aims to investigate the incidence of recurrent wheezing in preschool children presenting with first wheezing episode and identify the associated factors. Methods: The study is an observational prospective study conducted at the inpatient pediatric department. Patients admitted with first episode of wheezing were followed up as an outpatient approximately one week after hospital discharge and subsequently followed up by telephone 3-monthly with a structured questionnaire seeking information concerning recurrent wheezing, defined as having a second wheezing episode requiring bronchodilator within a 1-year period. Results: The total of 97 patients, aged 6 months to 5 years, were recruited from June 2014 to November 2015. Thirty-five patients were excluded because of inaccessibility for telephone follow-up. Amongst the remaining 62 patients, twenty-eight (45.2%) had recurrent wheezing within one year. The mean lapse duration was 4.7 ± 3.7 months after the first episode. Having an allergic sensitization to aeroallergen was a risk factor for recurrent wheezing (OR 2.48, 95%CI 1.81–3.4). Although not statistically significant, having an allergic sensitization to food seems to be another related factor (OR 2.36, 95%CI 1.75-3.18). Conclusion: The recurrent rate of wheezing was 45%, which was considerably significant. Allergic sensitization to aeroallergen might increase the risk. These patients should be followed up, especially within the first year after their first wheezing episode. en_US
dc.language.iso en en_US
dc.publisher NLM (Medline) en_US
dc.relation.uri http://doi.org/10.12932/AP-090217-0011
dc.rights © 2018 Asian Pacific Journal of Allergy and Immunology en_US
dc.title First episode of preschool wheeze requiring hospitalization: a prospective study on the chance of recurrence and associated factors en_US
dc.type Article en_US
dc.email.author No information provided
dc.email.author Jitladda.D@Chula.ac.th
dc.email.author Suchada.Sr@Chula.ac.th
dc.subject.keyword First wheezing en_US
dc.subject.keyword Preschool en_US
dc.subject.keyword Hospitalized en_US
dc.subject.keyword Recurrent en_US
dc.subject.keyword Incidence en_US
dc.subject.keyword Associated factors en_US
dc.identifier.DOI 10.12932/AP-090217-0011


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