Abstract:
Rice granules as major energy supply to humanity worldwide are utilized in many fields, such as food, medical, printing and plastic industries. In this thesis work, rice starch/granule is applied as hydrophilic drug (vancomycin) carrier to achieve the release. By confirmation on the stability of rice granules against to various treatments like alkali, acid and heating, as well as a-amylase, trypsin, and lipase, it is possible to use rice granules as 100% natural source to be the capsule and matrix getting the non-core-shell structure of the formation. The success of encapsulation is confirmed by the observations on crystalline, thermal properties and functional groups from XRD, TGA, and IR analysis. Release of vancomycin from rice granules was observed by experiments, but only 70% vancomycin encapsulated can be released out, another 30% is entrapped or combined with rice granule matrix very strong, leading the vancomycin kept inside starch matrix. In addition to aromatic oils encapsulations, the protective and released properties of rice granules are determined. The evaluation to the dishes with rice granules encapsulated with aromatic oils as seasonings by experts shows that dishes prepared by aromatic rice granules could achieve best results after 5 days storage when reheated by microwave-oven. A mathematical model is applied to explain the encapsulation process.
