Chemical constituents and biological activity of the fruits of Xylocarpus granatum Koen

Abstract

The preliminary bioassay results indicatied that crude extracts of the fruits and the seeds of Xylocarpus granatum Koen. were biologically active. Seven substances were isolated from the crude extract of the fruits. By means of physical properties, chemical reactions and spectroscopic data, all of them were elucidated their structural formulae as a mixture of long chain aliphatic esters, a mixture of long chain aliphatic alcohlos (C25,C27-30), a mixture of long chain carboxylic acids (C17-25,C27),7-oxo-7-deacetoxy gedunin,xyloccensin K (a new limonoid) and a mixture of steroidal glycosides. Besides all isolated substances obtained from the friuts,two additional unidentified limonoids could be isolated from the seeds of this plant. 7-0xo-7-deacetoxy gedunin and xyloccensin K exhibited an antifeedant activity of 80.69% and 66.29% against Greater Wax Moth,Galleria mellonella at dose level 4.0 mg.